APE1-IN-2
APE1-IN-2 is a Pt (IV) prodrug that selectively inhibits the DNA repair enzyme APE1. This action induces intracellular platinum accumulation, DNA damage response, and apoptosis, demonstrating anticancer activity in research models for oncology and DNA repair studies.
Product Specifications
CAS Number
2923433-95-6
Field of Research
Cell Biology
Smiles
O=[N+] (C1=CC=CC2=C1NC (C (O[Pt] ([NH3]) (Cl) (O) (Cl) [NH3]) =O) =C2) [O-]
Molecular Formula
C9H12Cl2N4O5Pt
Molecular Weight
522.21
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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