APE1-IN-2
APE1-IN-2 is a Pt (IV) prodrug that selectively inhibits the DNA repair enzyme APE1. This action induces intracellular platinum accumulation, DNA damage response, and apoptosis, demonstrating anticancer activity in research models for oncology and DNA repair studies.
Product Specifications
CAS Number
2923433-95-6
Field of Research
Cell Biology
Smiles
O=[N+] (C1=CC=CC2=C1NC (C (O[Pt] ([NH3]) (Cl) (O) (Cl) [NH3]) =O) =C2) [O-]
Molecular Formula
C9H12Cl2N4O5Pt
Molecular Weight
522.21
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
GTR15173565 1 Vial
Lentiviral mouse 1700102P08Rik shRNA (UAS) - Lentiviral mouse 1700102P08Rik shRNA (UAS, GFP) (100)
Sign In for Pricing
View Details K7013006 1.0 µg DNA
Fdps sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 1)
Sign In for Pricing
View Details 
GTR10471794 96 Well
Goat Conserved oligomeric Golgi complex subunit 8 (COG8) ELISA kit
Sign In for Pricing
View Details 
VAng-0242Lsx-1mgEcoli 1 mg (E. coli)
Recombinant Shigella Sonnei tolB Protein (aa 22-430)
Sign In for Pricing
View Details orb2548766 100 µL
Phospho-BRAF (Ser365) Rabbit Polyclonal Antibody (APC-Cy5.5)
Sign In for Pricing
View Details