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TrkA-IN-3

TrkA-IN-3 is a highly potent and subselective allosteric inhibitor of TrkA (IC50 = 22.4 nM) with >8000-fold selectivity over TrkB/C. Its profile makes it a valuable chemical probe for investigating TrkA-specific signaling in pain pathways, suitable for both in vitro biochemical assays and in vivo pain research models.

Product Specifications

CAS Number

3026111-73-6

Field of Research

Signal Transduction

Purity

98.37% (May vary between batches)

Smiles

O=C (O) C1=CN=C (C=2C=CC=CC2) C (=C1) NC (=O) C=3C=CC (=C (C3) C4=NN (C=C4) C) C (F) (F) F

Molecular Formula

C24H17F3N4O3

Molecular Weight

466.41

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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