Mps1-IN-5
Mps1-IN-5 is a potent and orally bioavailable Mps1 inhibitor (IC50 = 29 nM) . It exerts antiproliferative and antitumor activity by blocking Mps1 autophosphorylation, causing DNA damage, and inducing G2/M cell cycle arrest and apoptosis in cellular and animal models [1].
Product Specifications
CAS Number
2890819-31-3
Field of Research
Cell Biology, Signal Transduction
Smiles
CN1CCN (CC1) C2=CC=C (C=C2) NC3=NC4=C (C (N5N=C (C6=CC=CC=C65) N) =N3) C=CN4
Molecular Formula
C24H25N9
Molecular Weight
439.52
Storage Conditions
-20°C
Notes
For research use only.
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