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Mps1-IN-5

Mps1-IN-5 is a potent and orally bioavailable Mps1 inhibitor (IC50 = 29 nM) . It exerts antiproliferative and antitumor activity by blocking Mps1 autophosphorylation, causing DNA damage, and inducing G2/M cell cycle arrest and apoptosis in cellular and animal models [1].

Product Specifications

CAS Number

2890819-31-3

Field of Research

Cell Biology, Signal Transduction

Smiles

CN1CCN (CC1) C2=CC=C (C=C2) NC3=NC4=C (C (N5N=C (C6=CC=CC=C65) N) =N3) C=CN4

Molecular Formula

C24H25N9

Molecular Weight

439.52

Storage Conditions

-20°C

Notes

For research use only.

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