AXL-IN-14
AXL-IN-14 is a potent and orally bioavailable AXL inhibitor with an IC50 of 0.8 nM. It blocks Gas6-induced signaling, cell migration, and invasion by reducing p-AXL and p-AKT levels, demonstrating anti-tumor efficacy in both cellular and animal models.
Product Specifications
CAS Number
2947506-65-0
Field of Research
Signal Transduction
Smiles
CC (C) N1C=C (C (=O) C (=C1) C (=O) NC2=CC (=C (C=C2) OC3=C4C (=NC=C3) NC5=CC=CC=C5O4) F) C6=CC=C (C=C6) F
Molecular Formula
C32H24F2N4O4
Molecular Weight
566.55
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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