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AXL-IN-14

AXL-IN-14 is a potent and orally bioavailable AXL inhibitor with an IC50 of 0.8 nM. It blocks Gas6-induced signaling, cell migration, and invasion by reducing p-AXL and p-AKT levels, demonstrating anti-tumor efficacy in both cellular and animal models.

Product Specifications

CAS Number

2947506-65-0

Field of Research

Signal Transduction

Smiles

CC (C) N1C=C (C (=O) C (=C1) C (=O) NC2=CC (=C (C=C2) OC3=C4C (=NC=C3) NC5=CC=CC=C5O4) F) C6=CC=C (C=C6) F

Molecular Formula

C32H24F2N4O4

Molecular Weight

566.55

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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