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GSK3-IN-3

GSK3-IN-3 is a neuroprotective small molecule that acts as a non-ATP competitive GSK-3 inhibitor (IC50: 3.01 μM) and a selective inducer of Parkin-dependent mitophagy. It has demonstrated protective effects in cellular models, such as against 6-OHDA toxicity, supporting its research use in studying neurodegenerative pathways.

Product Specifications

CAS Number

331963-27-0

Product Name Alternative

Mitophagy, GSK-3, GSK3

Field of Research

Cell Biology, Signal Transduction, Stem Cell & Developmental Biology

Purity

98.16% (May vary between batches)

Solubility

DMSO:3.8 mg/mL (8.85 mM)

Smiles

C (C) N1C=2C (C (O) =C (C (NNC (CCCCCCCCCCC) =O) =O) C1=O) =CC=CC2

Molecular Formula

C24H35N3O4

Molecular Weight

429.55

Storage Conditions

-20°C

Notes

For research use only.

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