GSK3-IN-3
GSK3-IN-3 is a neuroprotective small molecule that acts as a non-ATP competitive GSK-3 inhibitor (IC50: 3.01 μM) and a selective inducer of Parkin-dependent mitophagy. It has demonstrated protective effects in cellular models, such as against 6-OHDA toxicity, supporting its research use in studying neurodegenerative pathways.
Product Specifications
CAS Number
331963-27-0
Product Name Alternative
Mitophagy, GSK-3, GSK3
Field of Research
Cell Biology, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.16% (May vary between batches)
Solubility
DMSO:3.8 mg/mL (8.85 mM)
Smiles
C (C) N1C=2C (C (O) =C (C (NNC (CCCCCCCCCCC) =O) =O) C1=O) =CC=CC2
Molecular Formula
C24H35N3O4
Molecular Weight
429.55
Storage Conditions
-20°C
Notes
For research use only.
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