Larotinib
Larotinib is a potent, orally bioavailable broad-spectrum tyrosine kinase inhibitor, exhibiting high potency against EGFR with an IC50 of 0.6 nM. It is utilized in cancer research for investigating oncogenic signaling pathways in both cellular and animal models of EGFR-driven malignancies.
Product Specifications
CAS Number
1438072-11-7
Product Name Alternative
Tyrosine Kinases, TyrosineKinases, BTK, IRAK, EGFR
Field of Research
Cardiovascular Research, Immunology & Inflammation, Signal Transduction
Purity
98.45% (May vary between batches)
Solubility
DMSO:60 mg/mL (122.71 mM)
Smiles
N (C=1C2=C (C=C (OC) C (OCCCN3C[C@@]4 ([C@] (C3) (OCCO4) [H]) [H]) =C2) N=CN1) C5=CC (Cl) =C (F) C=C5
Molecular Formula
C24H26ClFN4O4
Molecular Weight
488.94
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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