(-) SHIN2
(+) SHIN2 is a serine hydroxymethyltransferase (SHMT) inhibitor with antileukemic activity. Its enantiomer, (-) SHIN2, is the corresponding stereoisomer. Research demonstrates that (+) SHIN2 exhibits synergistic effects with Methotrexate in both in vitro and in vivo leukemia models.
Product Specifications
Smiles
CC (C) [C@] (C (C#N) =C (O1) N) (C2=CC (C#CCCCO) =CC (CO) =C2) C3=C1NN=C3C
Molecular Formula
C23H26N4O3
Molecular Weight
406.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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