GNE-2256
GNE-2256 (molecule 19) is a potent and orally bioavailable IRAK4 inhibitor with a K i of 1.4 nM and an IL-6 IC50 of 190 nM. This small molecule is a valuable research tool for investigating IRAK4-dependent signaling in autoimmune, inflammatory, and oncological research contexts, both in vitro and in vivo.
Product Specifications
CAS Number
2102170-43-2
Field of Research
Immunology & Inflammation, Signal Transduction
Purity
99.95% (May vary between batches)
Smiles
N (C (=O) C1=C2N (N=C1) C=CC=N2) C3=C (C=C4C (=C3) CN (C[C@H] (C (C) (C) O) F) C4=O) N5CCOCC5
Molecular Formula
C24H27FN6O4
Molecular Weight
482.51
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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