TP-030-2
TP-030-2 is a potent and selective inhibitor of RIPK1, demonstrating high affinity with a Ki of 0.43 nM in human systems and an IC50 of 100 nM in mouse models. This small molecule is a valuable research tool for studying necroptosis and inflammation in both cellular assays and in vivo experimental contexts.
Product Specifications
CAS Number
2095514-84-2
Field of Research
Cell Biology, Protein Biochemistry, Signal Transduction
Smiles
O=C1C=2C (=C (Br) N (CC3=CC=CC=C3) N2) CCN1[C@@H]4C (=O) N (C) C=5C (OC4) =CC=CC5
Molecular Formula
C23H21BrN4O3
Molecular Weight
481.34
Storage Conditions
-20°C
Notes
For research use only.
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