GLPG3970
GLPG3970 is an orally bioavailable, selective dual inhibitor of salt-inducible kinases 2 and 3 (SIK2/SIK3) . It demonstrates anti-inflammatory effects in preclinical models, supporting its research in autoimmune diseases such as psoriasis and rheumatoid arthritis through both in vitro and in vivo studies.
Product Specifications
CAS Number
2403733-82-2
Product Name Alternative
SIK2, SIK3
Field of Research
Signal Transduction
Purity
99.60% (May vary between batches)
Solubility
DMSO:128.8 mg/mL (255.3 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.54 mM)
Smiles
O=C1C=2C (OC) =CC (=CC2CCN1CC (F) (F) F) C3=CN=C4C=C (OCCN5CCOCC5) C=CN43
Molecular Formula
C25H27F3N4O4
Molecular Weight
504.5
Storage Conditions
-20°C
Notes
For research use only.
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