Aviculin
Aviculin is a lignan glycoside with potent anticancer activity, demonstrating an IC50 of 75.47 μM against MCF-7 breast cancer cells. It induces apoptosis via the intrinsic pathway by activating caspase-9/7, cleaving PARP, and increasing the Bax/Bcl-2 ratio, supporting its use in oncology research for mechanistic in vitro studies.
Product Specifications
CAS Number
156765-33-2
Field of Research
Cell Biology, Epigenetics & Chromatin, Molecular Biology, Protein Biochemistry
Smiles
C (O[C@H]1[C@H] (O) [C@H] (O) [C@@H] (O) [C@H] (C) O1) [C@@H]2[C@H] (C=3C (C[C@H]2CO) =CC (OC) =C (O) C3) C4=CC (OC) =C (O) C=C4
Molecular Formula
C26H34O10
Molecular Weight
506.54
Storage Conditions
-20°C
Notes
For research use only.
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