EDP-305
EDP-305 is a potent and selective oral FXR agonist, demonstrating EC50 values of 34 nM and 8 nM in different cellular assays. It shows consistent antifibrotic activity in research models for liver diseases, including primary biliary cholangitis (PBC) and non-alcoholic steatohepatitis (NASH), as supported by in vitro and in vivo studies.
Product Specifications
CAS Number
1933507-63-1
Field of Research
Metabolism Research
Purity
97.17% (May vary between batches)
Smiles
O[C@H]1[C@@]2 ([C@@] ([C@]3 (C) [C@] ([C@H]1CC) (C[C@H] (O) CC3) [H]) (CC[C@@]4 (C) [C@]2 (CC[C@@]4 ([C@@H] (CCNC (NS (=O) (=O) C5=CC=C (C (C) (C) C) C=C5) =O) C) [H]) [H]) [H]) [H]
Molecular Formula
C36H58N2O5S
Molecular Weight
630.92
Storage Conditions
-20°C
Notes
For research use only.
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