JMX0293
JMX0293 is a potent and selective STAT3 phosphorylation inhibitor with strong anti-tumor activity. It induces apoptosis in triple-negative breast cancer MDA-MB-231 cells in vitro (IC50 = 3.38 μM) and suppresses xenograft tumor growth in vivo, while exhibiting minimal toxicity to non-cancerous MCF-10A breast epithelial cells.
Product Specifications
Field of Research
Cell Biology
Smiles
CC (OC (NCCOC1=C (C=C (C=C1) Cl) C (N[C@@H] (C (C) C) C (NC2=C (C=C (C=C2) [N+] ([O-]) =O) Cl) =O) =O) =O) (C) C
Molecular Formula
C25H30Cl2N4O7
Molecular Weight
569.43
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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