CPT-Se4

CPT-Se4 is a selenium-modified camptothecin derivative that potently induces apoptosis in cancer cells by disrupting redox balance, elevating ROS, and depleting glutathione. It demonstrates broad cytotoxicity in vitro against multiple cancer cell lines, including HeLa and Hep G2, with IC50 values in the low micromolar range, supporting its investigation as an antitumor agent.