VT02956
VT02956 is a potent and selective LATS1/2 inhibitor (IC50 <1 nM) that targets the Hippo signaling pathway. It suppresses ESR1 expression and inhibits the growth of ER+ breast cancer cells and patient-derived organoids in vitro, making it a valuable research tool for studying Hippo pathway biology and oncology.
Product Specifications
CAS Number
2999763-09-4
Smiles
C1CN (CCC1CN) C2=NC (=NC3=C (C=CC=C32) C#CCO) C4=CC=NC=C4
Molecular Formula
C22H23N5O
Molecular Weight
373.45
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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