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VT02956

VT02956 is a potent and selective LATS1/2 inhibitor (IC50 <1 nM) that targets the Hippo signaling pathway. It suppresses ESR1 expression and inhibits the growth of ER+ breast cancer cells and patient-derived organoids in vitro, making it a valuable research tool for studying Hippo pathway biology and oncology.

Product Specifications

CAS Number

2999763-09-4

Smiles

C1CN (CCC1CN) C2=NC (=NC3=C (C=CC=C32) C#CCO) C4=CC=NC=C4

Molecular Formula

C22H23N5O

Molecular Weight

373.45

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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