TIM-063
TIM-063 is a potent, cell-permeable CaMKK inhibitor that acts by competing with ATP at the kinase's catalytic domain. It shows high selectivity with K (i) values of 0.35 μM for CaMKKα and 0.2 μM for CaMKKβ. This tool compound is widely used in vitro to study AMPK and calcium signaling pathways in metabolic and neurological research.
Product Specifications
CAS Number
2493978-38-2
Field of Research
Neuroscience
Smiles
N (=O) (=O) C1=C2C3=C (C=4N (C (=O) C3=CC=C2) C=5C (N4) =CC=CC5) C=C1O
Molecular Formula
C18H9N3O4
Molecular Weight
331.28
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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