NP10679
NP10679 is a potent, brain-penetrant, and pH-sensitive GluN2B-selective NMDA receptor antagonist with oral bioavailability. Its off-target activity includes inhibition of histamine H1 and hERG. This profile makes it a useful research tool for investigating mechanisms in epilepsy and ischemic stroke models, both in vitro and in vivo.
Product Specifications
CAS Number
2914889-88-4
Product Name Alternative
NMDA receptor, Histamine Receptor, HistamineReceptor, hERG, CYP
Field of Research
Immunology & Inflammation, Metabolism Research, Neuroscience, Pharmacology & Drug Discovery
Purity
99.43% (May vary between batches)
Solubility
DMSO:80 mg/mL (177.99 mM)
Smiles
O (C[C@@H] (CN1CCN (CC1) C2=CC=C (C (F) (F) F) C=C2) O) C=3C=C4C (=CC3) NC (=O) CC4
Molecular Formula
C23H26F3N3O3
Molecular Weight
449.47
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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