CZS-241
CZS-241 is a potent and selective oral PLK4 inhibitor (IC50=2.6 nM) with additional TRKA activity. It triggers S/G2 phase arrest and apoptosis, showing strong anti-leukemic effects in vitro while sparing normal cells, making it a valuable research tool for oncology and kinase biology studies.
Product Specifications
Field of Research
Cell Biology, Signal Transduction
Smiles
CC1=CC (=NN1) NC2=C3C=NN (C3=NC (=N2) NCC4=CC (=C (C=C4) Cl) C (=O) NC5=C (C=CC (=C5) F) F) C (C) C
Molecular Formula
C26H24ClF2N9O
Molecular Weight
551.98
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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