MK-8189
MK-8189 is a highly potent and selective pyrimidine-based inhibitor of PDE10A, exhibiting a Ki of 0.029 nM. This compound is a valuable research tool for investigating PDE10A's role in neurobiology, with applications in preclinical in vitro and in vivo studies relevant to schizophrenia and related CNS disorders.
Product Specifications
CAS Number
1424371-93-6
Product Name Alternative
MK8189
Field of Research
Metabolism Research
Purity
99.38% (May vary between batches)
Solubility
DMSO:100 mg/mL (261.45 mM)
Smiles
C (OC=1C=C (NCC2=NN=C (C) S2) N=C (C) N1) [C@@H]3[C@H] (C3) C4=CC=C (C) C=N4
Molecular Formula
C19H22N6OS
Molecular Weight
382.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![Donkey Polyclonal Donkey anti-Sheep IgG (H+L) Secondary Antibody [HRP]](https://cdn.genprice.uk/genprice/uk/genprice2.webp)
NBP1-75430 1 mg
Donkey Polyclonal Donkey anti-Sheep IgG (H+L) Secondary Antibody [HRP]
Sign In for Pricing
View Details K2697908 1.0 µg DNA
ZNF296 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 3)
Sign In for Pricing
View Details 
MBS1326018-01 0.02 mg (E-Coli)
Recombinant Gossypium hirsutum Histone H3.3 (HIS3)
Sign In for Pricing
View Details MBS1326018-02 0.1 mg (E-Coli)
Recombinant Gossypium hirsutum Histone H3.3 (HIS3)
Sign In for Pricing
View Details