PF-184
PF-184 is a highly selective IKK-2 inhibitor (IC50 = 37 nM) with minimal activity against IKK-1 and numerous other kinases. It is a valuable research tool for investigating NF-κB signaling in inflammatory diseases, including applications in both in vitro and in vivo models of asthma and COPD.
Product Specifications
Field of Research
Signal Transduction
Smiles
C[C@@]1 ([C@] (C) (CN (C2=NC=C (Cl) C (C (NC (C=C3) =CC4=C3CCC (C (C (N) =O) =N5) =C4N5C6=CC=C (F) C=C6) =O) =C2) C1) CO) CO
Molecular Formula
C32H32ClFN6O4
Molecular Weight
619.09
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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