RMS-07
RMS-07 is a potent and selective covalent inhibitor of MPS1 kinase (TTK), with an IC50 of 13.1 nM, targeting a unique cysteine in its hinge region. This small molecule is a valuable chemical probe for studying mitosis, chromosome segregation, and aneuploidy in both cellular and in vivo cancer research models.
Product Specifications
CAS Number
2645409-78-3
Field of Research
Signal Transduction
Smiles
C (NC1=C (CC) C=CC=C1CC) (=O) C2=C3N (C=4C (CC3) =CN=C (NC5=C (NC (C=C) =O) C=C (C=C5) N6CCN (C) CC6) N4) C=C2
Molecular Formula
C35H40N8O2
Molecular Weight
604.74
Storage Conditions
-20°C
Notes
For research use only.
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