RIG012
RIG012 is a potent small molecule inhibitor of the RIG-I receptor, exhibiting an IC50 of 0.71 μM in an ATPase activity assay. It effectively suppresses downstream antiviral signaling, including the expression of IFN-β and ISGs like hRsad2, making it a valuable tool for studying innate immune pathways in vitro.
Product Specifications
CAS Number
2642218-43-5
Product Name Alternative
RIG-I
Field of Research
Immunology & Inflammation
Purity
99.48% (May vary between batches)
Solubility
DMSO:36.43 mg/mL (101.36 mM)
Smiles
C (C) C1 (CC) C=2C (C=3C (C (=O) C2OCC4=CC=CC=C4) =CC=CC3) =NC1=O
Molecular Formula
C23H21NO3
Molecular Weight
359.42
Storage Conditions
-20°C
Notes
For research use only.
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