GSK761
GSK761 is a potent and selective SP140 inhibitor (IC50 = 77.79 nM) that suppresses pro-inflammatory macrophage differentiation and LPS-induced activation while promoting the generation of regulatory CD206+ macrophages, useful for studying immunomodulation in vitro.
Product Specifications
Field of Research
Epigenetics & Chromatin
Smiles
CC (C) (C) OCCC1=CC (=CC=C1) NC (=O) C2=CC=C (C=C2) C3=NC4=C (N3C) C=CC (=C4) C (=O) NC5=CC=CC (=C5) CCOC (C) (C) C
Molecular Formula
C40H46N4O4
Molecular Weight
646.82
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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