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GSK761

GSK761 is a potent and selective SP140 inhibitor (IC50 = 77.79 nM) that suppresses pro-inflammatory macrophage differentiation and LPS-induced activation while promoting the generation of regulatory CD206+ macrophages, useful for studying immunomodulation in vitro.

Product Specifications

Field of Research

Epigenetics & Chromatin

Smiles

CC (C) (C) OCCC1=CC (=CC=C1) NC (=O) C2=CC=C (C=C2) C3=NC4=C (N3C) C=CC (=C4) C (=O) NC5=CC=CC (=C5) CCOC (C) (C) C

Molecular Formula

C40H46N4O4

Molecular Weight

646.82

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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