FLDP-5

FLDP-5 is a BBB-penetrant curcuminoid analog that triggers ROS generation, DNA damage, and S-phase arrest, leading to potent anti-proliferative and anti-migratory effects in glioblastoma models like LN-18 cells. Its mechanism supports research in neuro-oncology and cancer therapeutics, with studies demonstrating efficacy in both in vitro and in vivo settings.