GK563
GK563 is a potent and selective inhibitor of Ca2+-independent phospholipase A2 GVIA (iPLA2β), with a 1 nM IC50 and >20,000-fold selectivity over GIVA cPLA2. It protects pancreatic β-cells from cytokine-induced apoptosis in vitro, highlighting its utility for researching autoimmune diabetes and inflammatory pathways.
Product Specifications
CAS Number
2351820-19-2
Field of Research
Cell Biology, Metabolism Research
Smiles
C (CC) [C@H]1[C@H] (CCCCC2=CC=CC=C2) C (=O) O1
Molecular Formula
C16H22O2
Molecular Weight
246.34
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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