JO146
JO146 is a dual protease inhibitor targeting Chlamydia trachomatis HtrA (CtHtrA; IC50 = 21.86 μM) and human neutrophil elastase (HNE; IC50 = 1.15 μM) . This small molecule is a research tool for studying bacterial pathogenesis and host inflammatory responses in vitro, with potential applications in infectious disease and protease research.
Product Specifications
CAS Number
130727-21-8
Field of Research
Protein Biochemistry
Smiles
P (C (NC (=O) [C@H]1N (C ([C@@H] (NC (OC (C) (C) C) =O) [C@H] (C) C) =O) CCC1) C (C) C) (OC2=CC=CC=C2) (OC3=CC=CC=C3) =O
Molecular Formula
C31H44N3O7P
Molecular Weight
601.67
Storage Conditions
-20°C
Notes
For research use only.
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