DB008
DB008 is a potent, selective, and cell-permeable PARP16 inhibitor with an IC50 of 0.27 μM, featuring an acrylamide warhead for covalent engagement. This tool compound enables the study of PARP16's roles in cellular stress responses, such as the unfolded protein response, in both in vitro and cellular research contexts.
Product Specifications
Field of Research
Epigenetics & Chromatin, Molecular Biology
Smiles
C=CC (=O) N1CCN (CC1) C (=O) C2=C (C=CC (=C2) CC3=NNC (=O) C4=C3C=C (C=C4) C#C) F
Molecular Formula
C25H21FN4O3
Molecular Weight
444.46
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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