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DB008

DB008 is a potent, selective, and cell-permeable PARP16 inhibitor with an IC50 of 0.27 μM, featuring an acrylamide warhead for covalent engagement. This tool compound enables the study of PARP16's roles in cellular stress responses, such as the unfolded protein response, in both in vitro and cellular research contexts.

Product Specifications

Field of Research

Epigenetics & Chromatin, Molecular Biology

Smiles

C=CC (=O) N1CCN (CC1) C (=O) C2=C (C=CC (=C2) CC3=NNC (=O) C4=C3C=C (C=C4) C#C) F

Molecular Formula

C25H21FN4O3

Molecular Weight

444.46

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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