W1131
W1131 is a potent STAT3 inhibitor that induces ferroptosis and inhibits tumor growth in models such as gastric cancer cell lines, organoids, and PDX models. It also reverses 5-FU resistance by modulating the IL6-JAK-STAT3 pathway, cell cycle, and oxidative phosphorylation, making it a valuable tool for oncology and drug resistance research.
Product Specifications
CAS Number
2740522-79-4
Field of Research
Cell Biology, Signal Transduction, Stem Cell & Developmental Biology
Smiles
N (C (=O) C=1OC (N (=O) =O) =CC1) C2=CC=C (C=3N4C (C=C (C=C4) C=5CCNCC5) =NC3) C=C2
Molecular Formula
C23H19N5O4
Molecular Weight
429.43
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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