(RS) -AMPA (monohydrate)

(RS) -AMPA ((±) -AMPA) monohydrate is a glutamate analogue and a potent and selective excitatory neurotransmitter L-glutamic acid agonist. (RS) -AMPA monohydrate does not interfere with binding sites for kainic acid or NMDA receptors[1][2].

Product Specifications

CAS Number

[76463-67-7]

Product Name Alternative

(±) -AMPA (monohydrate)

UNSPSC

12352005

Target

IGluR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/rs-ampa-monohydrate.html

Purity

99.90

Solubility

H2O : 5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(O)C(N)CC1=C(C)ONC1=O.[H]O[H]

Molecular Formula

C7H12N2O5

Molecular Weight

204.18

References & Citations

[1]Hösli L, et al. Effects of the glutamate analogue AMPA and its interaction with antagonists on cultured rat spinal and brain stem neurones. Neurosci Lett. 1983 Mar 28;36 (1) :59-62.|[2]Sommer B, et al. Flip and flop: a cell-specific functional switch in glutamate-operated channels of the CNS. Science. 1990 Sep 28;249 (4976) :1580-5.