β-NF-JQ1
β-NF-JQ1 is a PROTAC molecule that utilizes β-naphthoflavone to engage the AhR E3 ligase, directing it to degrade BRD-containing proteins. This bifunctional degrader demonstrates potent anticancer activity through targeted protein knockdown in cellular studies, making it a valuable tool for probing BRD protein function and PROTAC mechanisms in cancer research.
Product Specifications
CAS Number
2380000-55-3
Product Name Alternative
BRD, AhR, b-NF-JQ1, beta-NF-JQ1, PROTAC, β NF JQ1, βNFJQ1, β-NF-JQ1, β-NF-JQ-1
Field of Research
Epigenetics & Chromatin, Pharmacology & Drug Discovery
Purity
97.58% (May vary between batches)
Smiles
CC=1C2=C (N3C ([C@H] (CC (NCCOCCOCCOCC4=CC=C (C=C4) C=5OC=6C (C (=O) C5) =C7C (=CC6) C=CC=C7) =O) N=C2C8=CC=C (Cl) C=C8) =NN=C3C) SC1C
Molecular Formula
C45H42ClN5O6S
Molecular Weight
816.36
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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