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IDX184

IDX184 is a liver-targeted nucleotide prodrug and potent, orally active inhibitor of the HCV NS5B polymerase (IC50=0.31 μM) . It has demonstrated anti-HCV activity in research, showing utility in both in vitro enzymatic assays and in vivo models for studying hepatitis C virus replication and combination therapies.

Product Specifications

CAS Number

1036915-08-8

Product Name Alternative

HCV NS5B polymerase, HCV Protease, HCVProtease, IDX 184, IDX184, IDX-184

Field of Research

Infectious Disease & Virology, Protein Biochemistry

Purity

97.15% (May vary between batches)

Solubility

DMSO:50 mg/mL (79.79 mM)

Smiles

C[C@]1 (O) [C@H] (N2C3=C (N=C2) C (=O) N=C (N) N3) O[C@H] (COP (NCC4=CC=CC=C4) (OCCSC (C (CO) (C) C) =O) =O) [C@H]1O

Molecular Formula

C25H35N6O9PS

Molecular Weight

626.62

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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