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NM-3

NM-3 is an orally bioavailable small molecule with anti-angiogenic and anti-tumor properties. It functions as a radiation sensitizer in experimental models by inhibiting VEGF-induced endothelial cell proliferation and inducing ROS-mediated apoptosis. Its research applications include studying angiogenesis, tumor response to radiotherapy, and combination therapies in both in vitro and in vivo settings.

Product Specifications

CAS Number

181427-78-1

Product Name Alternative

Isocoumarin NM-3, NM 3, NM3, Apoptosis, ReactiveOxygenSpecies, Reactive Oxygen Species

Field of Research

Cell Biology, Immunology & Inflammation, Metabolism Research, Signal Transduction

Purity

99.00% (May vary between batches)

Solubility

DMSO:27.5 mg/mL (104.08 mM)

Smiles

O=C1C=2C (C=C (C (C (O) =O) C) O1) =CC (OC) =CC2O

Molecular Formula

C13H12O6

Molecular Weight

264.23

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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