NM-3
NM-3 is an orally bioavailable small molecule with anti-angiogenic and anti-tumor properties. It functions as a radiation sensitizer in experimental models by inhibiting VEGF-induced endothelial cell proliferation and inducing ROS-mediated apoptosis. Its research applications include studying angiogenesis, tumor response to radiotherapy, and combination therapies in both in vitro and in vivo settings.
Product Specifications
CAS Number
181427-78-1
Product Name Alternative
Isocoumarin NM-3, NM 3, NM3, Apoptosis, ReactiveOxygenSpecies, Reactive Oxygen Species
Field of Research
Cell Biology, Immunology & Inflammation, Metabolism Research, Signal Transduction
Purity
99.00% (May vary between batches)
Solubility
DMSO:27.5 mg/mL (104.08 mM)
Smiles
O=C1C=2C (C=C (C (C (O) =O) C) O1) =CC (OC) =CC2O
Molecular Formula
C13H12O6
Molecular Weight
264.23
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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