12 (S) -HEPE
12 (S) -HEPE is a 12-lipoxygenase-derived metabolite of eicosapentaenoic acid (EPA) . It is further metabolized by neutrophils to dihydroxy products and can competitively inhibit the 5-lipoxygenase pathway, reducing leukotriene synthesis. This mechanism underpins its research utility in studying the anti-inflammatory actions of omega-3 fatty acids in cellular and biochemical assays.
Product Specifications
CAS Number
116180-17-7
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Smiles
C (\[C@H] (C/C=C\C/C=C\CC) O) =C/C=C\C/C=C\CCCC (O) =O
Molecular Formula
C20H30O3
Molecular Weight
318.45
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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