12 (S) -HEPE
12 (S) -HEPE is a 12-lipoxygenase-derived metabolite of eicosapentaenoic acid (EPA) . It is further metabolized by neutrophils to dihydroxy products and can competitively inhibit the 5-lipoxygenase pathway, reducing leukotriene synthesis. This mechanism underpins its research utility in studying the anti-inflammatory actions of omega-3 fatty acids in cellular and biochemical assays.
Product Specifications
CAS Number
116180-17-7
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Smiles
C (\[C@H] (C/C=C\C/C=C\CC) O) =C/C=C\C/C=C\CCCC (O) =O
Molecular Formula
C20H30O3
Molecular Weight
318.45
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
E45H50597E1-100 100 µg
TNFAIP8 Protein, Human, Recombinant (His Tag)
Sign In for Pricing
View Details APR13017G 0.1mg
Monoclonal PTF1A Antibody (monoclonal) (M05), Clone: 1A2
Sign In for Pricing
View Details 
HK300691 200 Reactions
MIR1268b Human qPCR Template Standard (MI0016748)
Sign In for Pricing
View Details