12 (S) -HpETE

12 (S) -HpETE is a 12-lipoxygenase-derived eicosanoid from arachidonic acid. It acts as a signaling molecule in various research contexts, including studies of neuronal modulation, gene expression (e.g., c-fos/c-jun), vascular tone, and enzyme regulation (e.g., 5-LO activation and CaMKII inhibition) in both cellular and biochemical assays.