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TUG-499

TUG-499 is a potent and selective agonist for the free fatty acid receptor 1 (FFAR1/GPR40) with an EC50 of 7.39 nM. It exhibits high selectivity over related receptors like FFA2, FFA3, and PPARγ. This compound is a valuable research tool for investigating FFAR1-mediated insulin secretion in both in vitro and in vivo models of type 2 diabetes.

Product Specifications

CAS Number

1206629-08-4

Product Name Alternative

PPARγ, TUG 499, TUG499, TUG-499, FFA2, GPR40

Field of Research

Metabolism Research, Molecular Biology, Pharmacology & Drug Discovery

Purity

99.59% (May vary between batches)

Solubility

DMSO:22.5 mg/mL (70.28 mM) ;10% DMSO+90% Corn Oil:2 mg/mL (6.25 mM)

Smiles

C (#CC1=CC=C (CCC (O) =O) C=C1) C=2C=C (Cl) N=C (Cl) C2

Molecular Formula

C16H11Cl2NO2

Molecular Weight

320.17

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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