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Tyrphostin AG 538

Tyrphostin AG 538 is a cell-permeable, reversible, and competitive chalcone inhibitor of the IGF-1 receptor kinase with an IC50 of 400 nM. It is used in research to study IGF-1R signaling in cancer biology and has been applied in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

133550-18-2

Product Name Alternative

AG 538, AG538, AG-538, IGF1R, IGF-1R, Tyrphostin AG538, Tyrphostin AG-538, Tyrphostin AG 538

Field of Research

Signal Transduction

Purity

98.75% (May vary between batches)

Solubility

DMSO:4.5 mg/mL (15.14 mM)

Smiles

C (/C (=C/C1=CC (O) =C (O) C=C1) /C#N) (=O) C2=CC (O) =C (O) C=C2

Molecular Formula

C16H11NO5

Molecular Weight

297.26

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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