Tyrphostin AG 538
Tyrphostin AG 538 is a cell-permeable, reversible, and competitive chalcone inhibitor of the IGF-1 receptor kinase with an IC50 of 400 nM. It is used in research to study IGF-1R signaling in cancer biology and has been applied in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
133550-18-2
Product Name Alternative
AG 538, AG538, AG-538, IGF1R, IGF-1R, Tyrphostin AG538, Tyrphostin AG-538, Tyrphostin AG 538
Field of Research
Signal Transduction
Purity
98.75% (May vary between batches)
Solubility
DMSO:4.5 mg/mL (15.14 mM)
Smiles
C (/C (=C/C1=CC (O) =C (O) C=C1) /C#N) (=O) C2=CC (O) =C (O) C=C2
Molecular Formula
C16H11NO5
Molecular Weight
297.26
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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