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Fuzapladib

Fuzapladib (IS-741) is a phospholipase A2 inhibitor that suppresses Mac-1 (integrin) expression, preventing inflammatory cell adhesion and tissue infiltration. It has been investigated in experimental models, including canine and rodent studies, for acute pancreatitis and associated systemic inflammation.

Product Specifications

CAS Number

141283-87-6

Product Name Alternative

IS 741, IS741, IS-741, Fuzapladib, phospholipase A2

Field of Research

Metabolism Research, Signal Transduction

Purity

99.65% (May vary between batches)

Solubility

DMSO:3.8 mg/mL (10.02 mM)

Smiles

N (C (=O) C1CCCCC1) C2=C (NS (CC) (=O) =O) N=CC (C (F) (F) F) =C2

Molecular Formula

C15H20F3N3O3S

Molecular Weight

379.4

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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