Camlipixant
Camlipixant (BLU-5937) is a potent, selective, and competitive oral P2X3 receptor antagonist with an IC50 of 25 nM for the human P2X3 homotrimer. It is a research tool for investigating chronic cough mechanisms and has demonstrated antitussive efficacy in clinical studies for refractory chronic cough.
Product Specifications
CAS Number
1621164-74-6
Product Name Alternative
BLU 5937, BLU5937, BLU-5937, Camlipixant, P2XReceptor, P2X3, P2X Receptor
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
97.06% (May vary between batches)
Solubility
DMSO:22.5 mg/mL (49.08 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.36 mM)
Smiles
C (C1=C (N=C2N1C=CC (C) =C2) C3=C (F) C=C (C (NC) =O) C=C3F) [C@H]4CN (C (OC) =O) CCO4
Molecular Formula
C23H24F2N4O4
Molecular Weight
458.46
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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