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Butyzamide

Butyzamide is a novel, orally active small molecule thrombopoietin receptor (Mpl) agonist. It stimulates cellular proliferation and activates JAK/STAT and MAPK signaling pathways in vitro, and has demonstrated efficacy in elevating platelet counts in mouse xenotransplantation models.

Product Specifications

CAS Number

1110767-45-7

Product Name Alternative

Butyzamide, JAK, TPO, ThrombopoietinReceptor, Thrombopoietin Receptor

Field of Research

Cardiovascular Research, Epigenetics & Chromatin, Immunology & Inflammation, Signal Transduction, Stem Cell & Developmental Biology

Purity

98.71% (May vary between batches)

Solubility

DMSO:165 mg/mL (278.93 mM)

Smiles

O (C) C1=C (C=CC=C1C (OCCC) C (C) (C) C) C=2N=C (NC (=O) C3=CC (Cl) =C (/C=C (/C (O) =O) \C) C (Cl) =C3) SC2

Molecular Formula

C29H32Cl2N2O5S

Molecular Weight

591.55

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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