GS-829845
GS-829845 is the primary active metabolite of the JAK1 inhibitor Filgotinib. It exhibits a longer half-life and approximately 10-fold lower potency than its parent compound. This small molecule is used in research to investigate JAK-STAT signaling in inflammatory and autoimmune disease models, both in vitro and in vivo.
Product Specifications
CAS Number
1257705-09-1
Product Name Alternative
Drug Metabolite, DrugMetabolite, JAK1, GS 829845, GS829845, GS-829845
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology
Purity
99.78% (May vary between batches)
Solubility
DMSO:90 mg/mL (251.8 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (9.23 mM)
Smiles
Nc1nc2cccc (-c3ccc (CN4CCS (=O) (=O) CC4) cc3) n2n1
Molecular Formula
C17H19N5O2S
Molecular Weight
357.43
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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