Human DLL4 Protein, Fc Tag, premium grade (Flagship)
Human DLL4 Protein, Fc Tag, premium grade (Flagship) (DL4-H5255) is expressed from human 293 cells (HEK293) . It contains AA Ser 27 - Pro 524 (Accession # NP_061947.1) .
Product Specifications
Background
Delta-like protein 4 (DLL4) is also known as Drosophila Delta homolog 4 (Delta4), which contains one DSL domain and eight EGF-like domains. DLL4 is expressed in vascular endothelium. DLL4 is involved in the Notch signaling pathway as Notch ligand, which can activates NOTCH1 and NOTCH4. DLL4 is involved in angiogenesis and negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. DLL4 can bind to Notch-1 and Notch-4.
Specifications
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 80.7 kDa. The protein migrates as 90 kDa±3 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number
NP_061947.1
Expression Region
Ser 27 - Pro 524
Host
HEK293
Target
DLL4
Conjugation
Unconjugated
Tag
C-Fc
Source
Human
Stability
● -20°C to -70°C for 24 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
0.01 EU per μg
Purity
95%
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Molecular Weight
80.7 kDa
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
200ug*5
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/DL4-H5255.pdf
Species
Human
Curated Selection
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